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Genzyme cerezyme
Cerezyme, supplied by Genzyme, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cerezyme+imiglucerase/cerezyme/pm41580110-80-28-29
Average 86 stars, based on 1 article reviews
cerezyme - by Bioz Stars, 2026-09
86/100 stars

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Article Title: Drugmaker reaps what it sows with first plant-made biologic.
Article Snippet: Plus, it’s become an increasingly crowded space: Cerezyme (imiglucerase), a similar enzyme replacement therapy from the US biotech company Genzyme, currently dominates the market, with global sales of around $720 million in 2010, although shortages have recently plagued its distribution; and, in February 2010, another player—Ireland’s Shire—entered the field with VPRIV (velaglucerase alfa), which netted $143 million in its first year alone.

Article Title: Grow your own: Protalix BioTherapeutics produces drugs in carrot cells.
Article Snippet: According to Aviezer, Eleyso costs an estimated $200,000 annually versus Genzyme’s Cerezyme (imiglucerase; made from Chinese hamster ovary cells) and Shire’s Vpriv (velaglucerase alfa; made from human cell lines), which both cost about $250,000 a year.

Article Title: Functional screening of pharmacological chaperones via restoration of enzyme activity upon denaturation.
Article Snippet: Cerezyme/Imiglucerase! (Genzyme!Canada!

Article Title: Isofagomine Induced Stabilization of Glucocerebrosidase
Article Snippet: Cerezyme (Imiglucerase) was purchased from Genzyme Corporation (Cambridge, MA).

Article Title: J&J's billion dollar punt on anti-amyloid antibody.
Article Snippet: 679 Alzheimer’s—occur downstream from beta amyloid plaque formation.. Even if bapineuzumab fails, however, that basic thesis will not disappear, for other factors could be invoked to explain its downfall.. “You’re never quite sure whether you’re testing the hypothesis or testing the molecule, because you have to do both at once,” says Eric Siemers, medical director of Alzheimer’s research at Eli Lilly, of Indianapolis.

Article Title: Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases.
Article Snippet: A link between lysosomal storage diseases (LSDs) and neurodegenerative disorders associated with accumulation of presynaptic protein alpha-synuclein has been shown.. Particularly, Gaucher disease (GD) patients with a deficiency of the lysosomal enzyme glucocerebrosidase (GBA) and carriers of GBA mutations are at increased risk of Parkinson’s disease (PD).. It remains unclear whether this link is due to increased alpha-synuclein oligomerization.

Article Title: A case of hepatosplenomegaly.
Article Snippet: This mystery case starts with a common problem: palpable liver and spleen with normal function—not yet a puzzler because many infants will have these findings.. In good practice, follow up remains key to determine whether the organs will continue to enlarge, or if they will become nonpalpable as they do when the cause is viral.. In this case, the organs continue to increase in size causing a flight to the textbooks or the memory bank to help determine the cause.

Article Title: Neurodevelopmental Outcome after Hematopoietic Cell Transplantation in Inborn Errors of Metabolism: Current Considerations and Future Perspectives.
Article Snippet: The success of Cerezyme (imiglucerase, genzyme) for the treatment of Gaucher disease has led to the development of similar therapies for other LSDs.



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